Abstract | PURPOSE:
Vogt-Koyanagi-Harada syndrome is a bilateral, chronic, diffuse granulomatous panuveitis frequently associated with neurological, auditory, and integumentary manifestations. It is also one of the most common forms of uveitis among pigmented races including Chinese patients. METHODS: This article reviews the current developments of Vogt-Koyanagi-Harada syndrome, including epidemiology, etiology, clinical features, observational techniques, genetics, treatment, and prognosis. RESULTS: CONCLUSION: Although the prognosis for VKH syndrome was greatly improved, future prospective, controlled, multi-center studies are needed to determine the optimal treatment regime for this disease. The IL17/23 pathway may provide a novel therapeutic target to control inflammation in VKH syndrome.
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Authors | Wang Fang, Peizeng Yang |
Journal | Current eye research
(Curr Eye Res)
Vol. 33
Issue 7
Pg. 517-23
(Jul 2008)
ISSN: 1460-2202 [Electronic] England |
PMID | 18600484
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Topics |
- Humans
- Uveomeningoencephalitic Syndrome
(diagnosis, epidemiology, etiology, therapy)
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