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A comparison of florfenicol and tulathromycine for the treatment of undifferentiated fever in feedlot calves.

Abstract
The purpose of this study was to compare the relative cost-effectiveness of florfenicol with that of tulathromycin for treatment of undifferentiated fever (UF) in feedlot calves at ultra-high risk of developing UF that receive metaphylactic tulathromycin on arrival at the feedlot. Calves that received therapeutic florfenicol had lower overall mortality (P=.045) and bovine respiratory disease mortality (P=.050) compared with calves that received therapeutic tulathromycin, but no significant differences were detected in feedlot performance, carcass characteristics, or other animal health variables. There was a net advantage of Can$41.19/treated animal in the florfenicol group versus the tulathromycin group. This study demonstrates that it is more cost-effective to use florfenicol than tulathromycin for the initial treatment of UF in feedlot calves at ultra-high risk of developing UF that receive on-arrival metaphylactic tulathromycin.
AuthorsTye Perrett, Sameeh M Abutarbush, Brian K Wildman, Maria T Fuchs, Oliver C Schunicht, Colleen M Pollock, R Kent Fenton, G Kee Jim, P Timothy Guichon, Calvin W Booker, Janice Berg, Joe Roder, Mark Spire
JournalVeterinary therapeutics : research in applied veterinary medicine (Vet Ther) Vol. 9 Issue 2 Pg. 128-40 ( 2008) ISSN: 1528-3593 [Print] United States
PMID18597251 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Bacterial Agents
  • Disaccharides
  • Heterocyclic Compounds
  • florfenicol
  • Thiamphenicol
  • tulathromycin
Topics
  • Animals
  • Animals, Newborn
  • Anti-Bacterial Agents (economics, therapeutic use)
  • Bovine Respiratory Disease Complex (drug therapy, mortality)
  • Cattle
  • Cattle Diseases (drug therapy, mortality)
  • Cost-Benefit Analysis
  • Disaccharides (economics, therapeutic use)
  • Fever (drug therapy, mortality, veterinary)
  • Heterocyclic Compounds (economics, therapeutic use)
  • Thiamphenicol (analogs & derivatives, economics, therapeutic use)
  • Treatment Outcome

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