Virilizing ovarian tumor in a 14-year-old female with a prior familial multinodular goiter.

Abstract

A 14-year-old female presented with intermittent abdominal pain, deepening of voice and amenorrhoea for 4 months. Twelve months earlier she had had a thyroidectomy because of familial multinodular goiter and had, subsequently, received substitution with L-thyroxine. At the time of admission, a high serum testosterone level was detected. The dexamethasone suppression test confirmed the hormonal autonomy and magnetic resonance imaging (MRI) visualized a solid tumor within the left ovary. The pathological diagnosis after left salpingo-oophorectomy was Sertoli-Leydig cell tumor. The patient has remained disease-free for 6 years.

• Authors: Marek Niedziela
• Journal: Pediatric blood & cancer (Pediatr Blood Cancer) Vol. 51 Issue 4 Pg. 543-5 (Oct 2008) ISSN: 1545-5017 [Electronic] United States
• PMID: 18570301 (Publication Type: Case Reports, Journal Article)
• Copyright: (c) 2008 Wiley-Liss, Inc.

Topics

• Adolescent
• Female
• Goiter (pathology, surgery)
• Humans
• Magnetic Resonance Imaging
• Ovarian Neoplasms (pathology, surgery)
• Ovariectomy
• Thyroidectomy
• Virilism (pathology)