| Abstract | PURPOSE: To study the effect of botulinum toxin A injection in the management of paralytic exotropia resulting from acute traumatic third (oculomotor) nerve palsy. METHODS: Nine patients with acute traumatic partial third-nerve palsy of less than 2 months' duration were treated by injection of botulinum toxin A into the ipsilateral lateral rectus muscle. The horizontal deviation angles before and after the injections were recorded. A distance exotropia of less than 10(Delta) or absence of diplopia in the primary position at the last follow-up was defined as recovery. RESULTS: The mean preinjection deviation in the primary position was 48.3(Delta) of exotropia, and the mean postinjection deviation in the primary position was 14.2(Delta) at the last follow-up. Seven patients experienced recovery and regained single binocular vision in the primary position. The overall recovery rate was 77.8%. Two patients did not recover and subsequently underwent strabismus surgery. CONCLUSIONS: Patients with acute traumatic partial third-nerve palsy treated by injection of botulinum toxin A in the lateral rectus muscle showed marked recovery when injection was performed within 2 months of the onset of palsy. Botulinum toxin injection into the lateral rectus muscle may provide temporary relief of symptoms in some patients and seems to be a useful treatment option in cases of acute traumatic third nerve palsy in the short-term. |
| Authors | Mohammad Reza Talebnejad, Mohammad Sharifi, Mohammad Hosein Nowroozzadeh
(Affiliation: Department of Ophthalmology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. talebnejadmr at yahoo.com)
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| Journal | Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus
(J AAPOS)
Vol. 12
Issue 5
Pg. 510-3
(Oct 2008)
ISSN: 1528-3933 United States |
| PMID | 18558505
(Publication Type: Journal Article)
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