Abstract | BACKGROUND: Previous investigations of the biologic activities of dirhamnolipid alpha-L-rhamnopyranosyl-(1-2)alpha-L-rhamnopyranosyl-3-hydroxydecanoyl-3-hydroxydecanoic acid have demonstrated that it could be a novel therapeutic agent for wound healing and various immunologic and dermatologic conditions. OBJECTIVE: METHODS: The patient was a 90-year-old woman who developed a decubitus ulcer on her right buttock. The patient was initially treated by a standard procedure using pressure reduction, wound management, surgical intervention, and nutrition. The open, full-thickness wound progressed to a size of 10 x 7 cm, with evidence of tissue deterioration. The draining ulcer reached a dimension of 1 x 1.5 x 3 cm. The 0.1% dirhamnolipid ointment was administered at regular intervals, three times daily, by applying a thin layer of ointment directly to the wound area. Photographs were taken at regular 5-day intervals. RESULTS: CONCLUSION:
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Authors | Ante Piljac, Tamara Stipcević, Jasenka Piljac-Zegarac, Goran Piljac |
Journal | Journal of cutaneous medicine and surgery
(J Cutan Med Surg)
2008 May-Jun
Vol. 12
Issue 3
Pg. 142-6
ISSN: 1203-4754 [Print] United States |
PMID | 18544299
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Glycolipids
- Ointments
- rhamnolipid hemolysin, Pseudomonas aeruginosa
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Topics |
- Aged, 80 and over
- Buttocks
- Chronic Disease
- Female
- Glycolipids
(therapeutic use)
- Humans
- Ointments
- Pressure Ulcer
(drug therapy)
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