HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Comparison of live avirulent M-9, Minnesota, and CU fowl cholera vaccines.

Abstract
The M-9 and Minnesota (MN) avirulent Pasteurella multocida vaccines were evaluated and compared with the Clemson University (CU) vaccine, which had been shown to be highly effective in preventing fowl cholera in turkeys. Neither the M-9 nor the MN vaccine given in the drinking water was as effective as the CU vaccine in protecting turkeys against challenge with virulent P. multocida. When grown in brain-heart infusion (BHI) agar as recommended, the M-9 was not as efficacious as when it was grown in BHI broth. The M-9 was as effective as the CU vaccine only when grown in BHI broth and given at 10 times the standard dosage. Injection of the M-9 vaccine into the air spaces of the head at a site near the caudal rim of the ear after one vaccination in the drinking water was not as effective for hyperimmunizing potential breeders as was the CU vaccine injected at the same site. A microtiter agglutination test demonstrated a significant (P less than 0.05) correlation between the level of anti-P. multocida antibody found 1 week after vaccination and survival after challenge with virulent P. multocida.
AuthorsR C Friedlander, L D Olson, E L McCune
JournalAvian diseases (Avian Dis) 1991 Apr-Jun Vol. 35 Issue 2 Pg. 251-6 ISSN: 0005-2086 [Print] UNITED STATES
PMID1854311 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Antibodies, Bacterial
  • Bacterial Vaccines
Topics
  • Administration, Oral
  • Animals
  • Antibodies, Bacterial (blood)
  • Bacterial Vaccines (administration & dosage, immunology)
  • Drinking
  • Female
  • Injections (veterinary)
  • Pasteurella (immunology)
  • Pasteurella Infections (prevention & control, veterinary)
  • Poultry Diseases (prevention & control)
  • Turkeys
  • Vaccination (veterinary)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: