Abstract | OBJECTIVE: METHOD: The expression of BRMS1 mRNA was examined by using RT-PCR method which take beta-actin mRNA as reference template in 66 cases of supraglottic cancer tissues and their adjacent normal mucosa tissues (ANT). RESULT: The expression of BRMS1 mRNA in the tissues of supraglottic cancer is lower significantly than that in the tissues of ANT ( P<0.05). There is correlation between BRMS1 mRNA expression and the clinical stage, differentiation and cervical lymph node metastasis in the laryngeal supraglottic cancers (P<0.05). There is no correlation between BRMS1 mRNA expression and sex and age. CONCLUSION:
|
Authors | Xiaoyu Li, Xing Guo, Fucai Li, Xiaotian Li, Chao Guan, Huaian Yang, Zimin Pan, Chanyuanz Li, Zhong Ren |
Journal | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
(Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi)
Vol. 22
Issue 6
Pg. 241-4
(Mar 2008)
ISSN: 2096-7993 [Print] China |
PMID | 18533556
(Publication Type: English Abstract, Journal Article)
|
Chemical References |
- BRMS1 protein, human
- Neoplasm Proteins
- RNA, Messenger
- Repressor Proteins
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
(metabolism, pathology)
- Female
- Humans
- Laryngeal Mucosa
(metabolism, pathology)
- Laryngeal Neoplasms
(metabolism, pathology)
- Lymphatic Metastasis
- Male
- Middle Aged
- Neoplasm Proteins
(metabolism)
- RNA, Messenger
(genetics)
- Repressor Proteins
|