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[A comparative study of sphingolipids in transplanted melanomas with high and low metastatic activity].

Abstract
The content of sphingolipids in M3 and B16/F10 melanomas with a high metastatic potential and in Claudman's and B16/F1 melanomas with a low metastatic potential was studied. It was shown that the content of total lipid-bound sialic acids and ganglioside GM3 in melanomas with a high metastatic potential is considerably higher than that in melanomas with a low metastatic potential. On the other hand, the ceramide to glucosylceramide molar ratio is higher in melanomas with a low metastatic potential. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2008, vol. 34, no. 2; see also http://www.maik.ru.
AuthorsA G Kandyba, A M Kozlov, O G Somova, E V Diatlovitskaia
JournalBioorganicheskaia khimiia (Bioorg Khim) 2008 Mar-Apr Vol. 34 Issue 2 Pg. 252-5 ISSN: 0132-3423 [Print] Russia (Federation)
PMID18522282 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Sphingolipids
Topics
  • Animals
  • Melanoma, Experimental (metabolism, secondary)
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred DBA
  • Neoplasm Transplantation
  • Sphingolipids (metabolism)

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