Abstract |
The G-4260, IR-N, M-6, and M-8 strains of avian nephritis virus (ANV) were inoculated orally into 1-day-old specific-pathogen-free chicks of the line PDL-1 for pathological and serological study. Five of 15 chicks inoculated with the G-4260 strain died with visceral urate depositions. One of 15 chicks each inoculated with the M-6 and M-8 strains died with nephrosis and visceral urate deposition, respectively. No chicks inoculated with the IR-N strain died. Mean body weights of ANV-inoculated chicks, except for the IR-N-inoculated chicks, at 14 days postinoculation (PI) were significantly lower than those of control chicks (P less than 0.01). However, interstitial nephritis was observed in all ANV-inoculated birds that were histopathologically examined at 14 days PI. In the serological study, the G-4260 and IR-N strains were classified as the same serotype, and the M-6 and M-8 strains were classified as a different serotype from the G-4260 and IR-N strains. These results indicate that there at least two serotypes of ANV and its strains differ in pathogenicity.
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Authors | J Shirai, K Nakamura, K Shinohara, H Kawamura |
Journal | Avian diseases
(Avian Dis)
1991 Jan-Mar
Vol. 35
Issue 1
Pg. 49-54
ISSN: 0005-2086 [Print] United States |
PMID | 1851420
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Animals
- Antigens, Viral
(analysis)
- Body Weight
- Chickens
- Cross Reactions
- Fluorescent Antibody Technique
- Kidney
(microbiology, pathology)
- Neutralization Tests
- Picornaviridae
(immunology, pathogenicity)
- Picornaviridae Infections
(microbiology, veterinary)
- Poultry Diseases
(microbiology)
- Specific Pathogen-Free Organisms
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