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A comparison of 2 vaccination programs in feedlot calves at ultra-high risk of developing undifferentiated fever/bovine respiratory disease.

AbstractThe aim of this study was to compare 2 vaccination programs in feedlot calves at ultra-high risk of developing undifferentiated fever (UF)/bovine respiratory disease (BRD). At feedlot arrival, 3882 calves were enrolled in the study and randomly allocated to 2 groups, which were housed by group in 12 pens. At the time of allocation, 1 group (MLV3-BT2) received a multivalent, modified-live viral vaccine containing infectious bovine rhinotracheitis virus (IBRV) and types I and II bovine viral diarrhea virus (BVDV), as well as a Mannheimia haemolytica (MH) and Pasteurella multocida bacterin-toxoid. The other group (MLV4-BT1) received a vaccine containing IIBRV, type I BVDV, bovine respiratory syncytial virus, and parainfluenza-3 virus, as well as a MH bacterin-toxoid. At an average of 69 days post arrival, the groups received their respective viral vaccines. The initial UF treatment, overall chronicity, overall wastage, overall mortality, and BRD mortality rates were significantly (P < 0.05) lower in the MLV3-BT2 group than in the MLV4-BT1 group. Average daily gain and the proportions of yield grade Canada 3 and quality grade E carcasses were significantly (P < 0.05) higher in the MLV3-BT2 group than in the MLV4-BT1 group. No significant (P > or = 0.05) difference in the dry matter intake to gain ratio was detected between the 2 groups. In economic terms, there was a net advantage of $20.86 CDN/animal in the MLV3-BT2 group. This study demonstrates that it is more cost effective to use an MLV3-BT2 vaccination program than a MLV4-BT1 vaccination program in feedlot calves at ultra-high risk of developing UF/BRD.
AuthorsBrian K Wildman, Tye Perrett, Sameeh M Abutarbush, P Timothy Guichon, Tom J Pittman, Calvin W Booker, Oliver C Schunicht, R Kent Fenton, G Kee Jim (Affiliation: Feedlot Health Management Services Ltd., PO Box 140, Okotoks, Alberta T1S 2A2.)
JournalThe Canadian veterinary journal. La revue vétérinaire canadienne (Can Vet J) Vol. 49 Issue 5 Pg. 463-72 (May 2008) ISSN: 0008-5286 Canada
PMID18512457 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Bacterial Vaccines
  • Vaccines, Combined
  • Viral Vaccines
Topics
  • Animals
  • Animals, Newborn
  • Bacterial Vaccines (administration & dosage)
  • Body Composition
  • Bovine Respiratory Disease Complex (prevention & control)
  • Cattle (growth & development)
  • Cattle Diseases (prevention & control)
  • Diarrhea Viruses, Bovine Viral (immunology)
  • Mannheimia haemolytica (immunology)
  • Parainfluenza Virus 3, Bovine (immunology)
  • Pasteurella multocida (immunology)
  • Random Allocation
  • Respiratory Syncytial Virus, Bovine (immunology)
  • Risk Factors
  • Vaccination (veterinary)
  • Vaccines, Combined
  • Viral Vaccines (administration & dosage)
  • Weight Gain