Abstract | PURPOSE: To compare the effect of ultrasound (US) phacoemulsification and AquaLase liquefaction (Alcon Laboratories) cataract surgery on the macula using optical coherence tomography (OCT). SETTING: Department of Ophthalmology, Queen Mary's Hospital, London, United Kingdom. METHODS: Sixty-three patients having cataract surgery were randomized to receive US phacoemulsification or AquaLase liquefaction cataract surgery. Macular thickness and volume were evaluated by OCT preoperatively and 2 and 6 weeks postoperatively. The primary outcomes were OCT central macular thickness and best corrected visual acuity at 6 weeks. Secondary outcomes were OCT macular volume and perioperative and postoperative complications. RESULTS: Over the 6-week study, the median increase in foveal thickness in the study eye compared with that in the fellow eye was 11 microm (interquartile range [IQR] -21 to 23 microm) in the AquaLase group and 17 microm (IQR -11 to 33 microm) in the phacoemulsification group (P = .229). A subgroup analysis of diabetic patients found a median increase in foveal thickness in the study eye versus the fellow eye of 2 microm (IQR -14 to 23 microm) in the AquaLase group and 29 microm (IQR 11 to 41 microm) in the phacoemulsification group (P = .07). CONCLUSIONS:
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Authors | Allon Barsam, Aman Chandra, Catey Bunce, Laurence A Whitefield |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 34
Issue 6
Pg. 991-5
(Jun 2008)
ISSN: 0886-3350 [Print] United States |
PMID | 18499007
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Topics |
- Aged
- Aged, 80 and over
- Cataract Extraction
(adverse effects, methods)
- Double-Blind Method
- Female
- Humans
- Lens Implantation, Intraocular
- Lenses, Intraocular
- Macula Lutea
(pathology)
- Macular Edema
(diagnosis, prevention & control)
- Male
- Middle Aged
- Phacoemulsification
(adverse effects, methods)
- Postoperative Complications
- Prospective Studies
- Tomography, Optical Coherence
- Visual Acuity
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