[A case of small cell carcinoma of the lung responding well to oral etoposide therapy].

Abstract

A case of recurrent small cell carcinoma of the lung, accompanied by intraperitoneal metastasis, was orally treated with etoposide (50 mg/day) for 3 consecutive weeks. Subjective symptoms such as abdominal pain began to improve one week after the start of treatment. After three weeks of treatment, these symptoms disappeared completely, and CT findings also improved. The serum NSE level, which was as high as 89.5 ng/ml before treatment, fell to 8.7 ng/ml after 3 weeks of treatment. The patient is now being followed at the outpatient clinic of our hospital. As adverse reactions to the drug, alopecia and leukopenia were observed. The leukopenia appeared in the third week of treatment, but the white blood cell count returned to normal soon after the drug was discontinued.

• Authors: Y Nakaoka, M Haraguchi, T Fujii, N Adachi, T Komatsu, K Ota, N Kurihara
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 18 Issue 4 Pg. 637-9 (Apr 1991) ISSN: 0385-0684 [Print] Japan
• PMID: 1849393 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Etoposide

Topics

• Administration, Oral
• Carcinoma, Small Cell (drug therapy, secondary)
• Drug Administration Schedule
• Etoposide (administration & dosage)
• Female
• Humans
• Lung Neoplasms (drug therapy, pathology)
• Middle Aged
• Peritoneal Neoplasms (secondary)