Familial alopecia areata and chronic thrombocytopenia.

Abstract

Alopecia areata (AA) has a strong hereditary component and is associated with a number of other autoimmune diseases. There is no established relationship between AA and any of the congenital thrombocytopenias. We report a family in which multiple members are affected with AA and with a hereditary thrombocytopenia, most consistent with pseudo-von Willebrand disease. This raises the possibility of a genetic association between AA and one or more of the inherited thrombocytopenias, possibly both related to mutations in genes on chromosome 17.

• Authors: Ammar M Ahmed, Nazila Barahmani, Madeleine Duvic, National Alopecia Areata Registry
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 58 Issue 5 Suppl 1 Pg. S75-7 (May 2008) ISSN: 1097-6787 [Electronic] United States
• PMID: 18489053 (Publication Type: Case Reports, Journal Article)

Topics

• Alopecia Areata (complications, genetics)
• Chronic Disease
• Family Health
• Female
• Humans
• Male
• Middle Aged
• Pedigree
• Thrombocytopenia (complications, genetics)