Anaesthesia for Angelman syndrome.

Abstract

We describe the administration of anaesthesia to a patient with Angelman syndrome, which is characterised by an abnormality of chromosome 15, where a subunit of the GABA receptor is coded. This has far-reaching anaesthetic implications as many drugs used in anaesthesia are thought to act via GABA receptors. Our patient had an uneventful peri-operative period and was discharged home on the second postoperative day.

• Authors: K R Ramanathan, D Muthuswamy, B J Jenkins
• Journal: Anaesthesia (Anaesthesia) Vol. 63 Issue 6 Pg. 659-61 (Jun 2008) ISSN: 1365-2044 [Electronic] England
• PMID: 18477280 (Publication Type: Case Reports, Journal Article)

Chemical References

• Receptors, GABA

Topics

• Anesthesia, Inhalation (methods)
• Angelman Syndrome (genetics, surgery)
• Child, Preschool
• Chromosomes, Human, Pair 15 (genetics)
• Humans
• Male
• Receptors, GABA (genetics)
• Submandibular Gland (surgery)