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Deuterium oxide, dimethylsulfoxide and heat shock confer protection against hydrostatic pressure damage in yeast.

Abstract
Deuterium oxide, dimethylsulfoxide (Me2SO) and heat shock treatment were all significantly effective at baro-injury as measured by plating efficiency after decompression. The content of unfreezable cell water was observed to increase during heat treatment, and this increase was associated with increase in viability.
AuthorsY Komatsu, K Obuchi, H Iwahashi, S C Kaul, M Ishimura, G M Fahy, W F Rall
JournalBiochemical and biophysical research communications (Biochem Biophys Res Commun) Vol. 174 Issue 3 Pg. 1141-7 (Feb 14 1991) ISSN: 0006-291X [Print] United States
PMID1847626 (Publication Type: Journal Article)
Chemical References
  • Heat-Shock Proteins
  • Water
  • Deuterium
  • Deuterium Oxide
  • Dimethyl Sulfoxide
Topics
  • Deuterium (pharmacology)
  • Deuterium Oxide
  • Dimethyl Sulfoxide (pharmacology)
  • Freezing
  • Heat-Shock Proteins (biosynthesis, isolation & purification)
  • Hot Temperature
  • Hydrostatic Pressure
  • Saccharomyces cerevisiae (drug effects, physiology)
  • Water (pharmacology)

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