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Survival and Histopathological Study of Animals Bearing Ehrlich Tumor Treated With a Rhodium(II) Amidate.

Abstract
The survival of 90% of a tumor-bearing population treated with the complex Rh(2) (CF(3)CONH)(4) was examined and the pharmacological parameter Surv(90) determined. Histopathological alterations raised for this drug in several tissues were studied in Balb-c mice. A Surv(90) dose of 3.8x 10(-5) mol/kg was found.
AuthorsB P Espósito, S B Zyngier, R Najjar, R P Paes, S M Ueda, J C Barros
JournalMetal-based drugs (Met Based Drugs) Vol. 6 Issue 1 Pg. 17-8 ( 1999) ISSN: 0793-0291 [Print] United States
PMID18475875 (Publication Type: Journal Article)

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