Abstract |
Nitric oxide has varied effects on human breast cancer cells. At low concentration (micromolar range) it increases proliferation by increasing synthesis of some cells cycle protein and in higher concentration (nanomolar range) it leads to cytostasis or apoptosis by decreasing the translation of some cell cycle proteins.
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Authors | Shehla Pervin, Rajan Singh, Gautam Chaudhuri |
Journal | Nitric oxide : biology and chemistry
(Nitric Oxide)
Vol. 19
Issue 2
Pg. 103-6
(Sep 2008)
ISSN: 1089-8611 [Electronic] United States |
PMID | 18474257
(Publication Type: Journal Article, Review)
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Chemical References |
- Cell Cycle Proteins
- Nitric Oxide
- N(omega)-hydroxyarginine
- Arginine
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Topics |
- Apoptosis
- Arginine
(analogs & derivatives, metabolism)
- Breast Neoplasms
(pathology)
- Cell Cycle Proteins
- Cell Proliferation
- Female
- Humans
- Nitric Oxide
(physiology)
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