Abstract |
A randomized clinical trial was undertaken to investigate the relative efficacy of rational-emotive behavior therapy (REBT), cognitive therapy (CT), and pharmacotherapy in the treatment of 170 outpatients with nonpsychotic major depressive disorder. The patients were randomly assigned to one of the following: 14 weeks of REBT, 14 weeks of CT, or 14 weeks of pharmacotherapy ( fluoxetine). The outcome measures used were the Hamilton Rating Scale for Depression and the Beck Depression Inventory. No differences among treatment conditions at posttest were observed. A larger effect of REBT (significant) and CT (nonsignificant) over pharmacotherapy at 6 months follow-up was noted on the Hamilton Rating Scale for Depression only.
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Authors | Daniel David, Aurora Szentagotai, Viorel Lupu, Doina Cosman |
Journal | Journal of clinical psychology
(J Clin Psychol)
Vol. 64
Issue 6
Pg. 728-46
(Jun 2008)
ISSN: 0021-9762 [Print] United States |
PMID | 18473339
(Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | (c) 2008 Wiley Periodicals, Inc. |
Chemical References |
- Serotonin Uptake Inhibitors
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Topics |
- Behavior Therapy
(methods)
- Cognitive Behavioral Therapy
- Depressive Disorder, Major
(drug therapy, psychology, therapy)
- Drug Administration Schedule
- Follow-Up Studies
- Humans
- Longitudinal Studies
- Models, Psychological
- Patient Compliance
- Personality Inventory
- Prospective Studies
- Psychiatric Status Rating Scales
- Selective Serotonin Reuptake Inhibitors
(therapeutic use)
- Treatment Outcome
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