Reducing the economic burden of HPV-related diseases.

Abstract

Human papillomavirus (HPV) infection is a common sexually transmitted infection that is often acquired at the onset of sexual activity. Risk factors include younger age at time of sexual debut, sexual behavior, intact foreskin, and immunologic status. Persistent infection with high-risk oncogenic HPV types (especially 16 and 18) is associated with cervical cancer, other anogenital diseases, as well as some head and neck cancers. Infection with low-risk HPV types is associated with genital warts, low-grade dysplasias, and recurrent respiratory papillomatosis. Screening and management of HPV-related diseases incur high healthcare costs. Whereas routine screening of female patients with Papanicolaou tests helps prevent advanced stages of cancer through early detection and treatment, the recently developed HPV L1 capsid protein virus-like particle vaccines offer an option for prevention of HPV-related diseases, including cervical cancer.

• Authors: Edward John Mayeaux Jr
• Journal: The Journal of the American Osteopathic Association (J Am Osteopath Assoc) Vol. 108 Issue 4 Suppl 2 Pg. S2-7 (Apr 2008) ISSN: 1945-1997 [Electronic] United States
• PMID: 18463361 (Publication Type: Journal Article, Review)

Topics

• Female
• Human papillomavirus 16
• Human papillomavirus 18
• Humans
• Mass Screening (economics)
• Papillomavirus Infections (diagnosis, economics, prevention & control)
• Risk Factors
• United States