| Abstract | Adult-onset Still's disease (AOSD) is a rheumatoid disorder characterized by high fever, polyarthritis, leukocytosis, hyperferritinaemia, and mild liver involvement. We describe the case of a patient with AOSD with severe liver dysfunction. His serum levels of interleukin-10 and 18 showed a similar trend to his disease activity. Drug lymphocyte stimulation tests were positive for three drugs in the patient. Hypercytokinaemia was controlled by plasma exchange therapy. |
| Authors | Tomoki Ito, Yoshio Ozaki, Keiko Shimamoto, Hideki Amuro, Tsutomu Tanijiri, Takashi Yokoi, Yonsu Son, Kenichirou Tajima, Shirou Fukuhara
(Affiliation: First Department of Internal Medicine, Kansai Medical University, 10-15 Fumizono-cho, Moriguchi, Osaka, 570-8506, Japan.)
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| Journal | Modern rheumatology / the Japan Rheumatism Association
(Mod Rheumatol)
Vol. 18
Issue 4
Pg. 407-10
( 2008)
ISSN: 1439-7595 Japan |
| PMID | 18443740
(Publication Type: Journal Article)
|
