Paradoxical response to levalbuterol.

Abstract

Asthma is a common condition that can substantially affect patients' quality of life. Although several drugs, most commonly beta-adrenergic agonists, alleviate symptoms of asthma, they may cause paradoxical bronchospasm or paradoxical bronchoconstriction. Levalbuterol hydrochloride-a pure form of the (R)-stereoisomer in racemic albuterol-eliminates the adrenergic properties that can cause such adverse effects. However, we report a case of paradoxical bronchoconstriction in a 36-year-old man who was recently diagnosed as having new-onset asthma and was treated with levalbuterol.

• Authors: Sarah E Broski, Dennis E Amundson
• Journal: The Journal of the American Osteopathic Association (J Am Osteopath Assoc) Vol. 108 Issue 4 Pg. 211-3 (Apr 2008) ISSN: 1945-1997 [Electronic] United States
• PMID: 18443029 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenergic beta-Agonists
• Albuterol

Topics

• Adrenergic beta-Agonists (administration & dosage, adverse effects)
• Adult
• Albuterol (administration & dosage, adverse effects)
• Asthma (drug therapy)
• Bronchial Diseases (chemically induced)
• Constriction, Pathologic (chemically induced)
• Humans
• Male
• Metered Dose Inhalers