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Olopatadine 0.2% ophthalmic solution: the first ophthalmic antiallergy agent with once-daily dosing.

AbstractBACKGROUND:
Olopatadine 0.2% is the first topical ophthalmic antihistamine/mast cell stabilizer indicated for once-daily dosing.
OBJECTIVE:
This review provides a comprehensive description of the pharmacology of the olopatadine molecule, as well as of the clinical efficacy, tolerability, and safety of olopatadine 0.2% ophthalmic solution.
METHODS:
References cited in this review were obtained from the PubMed biomedical literature database. Also included were several posters presented at nationally renowned ophthalmology-related conferences.
RESULTS/CONCLUSION:
Olopatadine 0.2% was found to be a safe and effective medication for the reduction of itching with a duration of action of up to 24 h. The added convenience of a once-a-day dosing regimen is a major advancement in this drug class.
AuthorsMark B Abelson, Paul J Gomes
JournalExpert opinion on drug metabolism & toxicology (Expert Opin Drug Metab Toxicol) Vol. 4 Issue 4 Pg. 453-61 (Apr 2008) ISSN: 1742-5255 [Print] England
PMID18433347 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Allergic Agents
  • Dibenzoxepins
  • Histamine H1 Antagonists, Non-Sedating
  • Ophthalmic Solutions
  • Olopatadine Hydrochloride
Topics
  • Anti-Allergic Agents (adverse effects, therapeutic use)
  • Clinical Trials as Topic
  • Conjunctivitis, Allergic (drug therapy, physiopathology)
  • Dibenzoxepins (adverse effects, therapeutic use)
  • Histamine H1 Antagonists, Non-Sedating (adverse effects, therapeutic use)
  • Humans
  • Olopatadine Hydrochloride
  • Ophthalmic Solutions (adverse effects, therapeutic use)
  • Treatment Outcome

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