| Abstract | The influence of Acnevac vaccine on immune responses of CBA mice was tested. Acnevac, the vaccine used in a treatment of patient with acne vulgaris, was produced by a Cracow Sera and Vaccines Manufacturer from cultures of Propionibacteria-strains. It was shown that Acnevac has strong immunomodulatory properties. It strongly stimulates humoral responses, has moderate effect on cell-mediated immune responses and it also activates peritoneal macrophages to release TNF-alpha. |
| Authors | J Marcinkiewicz, K Bryniarski, B Nowak, D Dzielska, F Payerhin
(Affiliation: Katedra Immunologii AM Krakowie.)
|
| Journal | Medycyna doświadczalna i mikrobiologia
(Med Dosw Mikrobiol)
Vol. 43
Issue 3-4
Pg. 167-74
( 1991)
ISSN: 0025-8601 POLAND |
| Vernacular Title | Immunomodulacyjne właściwości szczepionki Acnevac. |
| PMID | 1840429
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
| Chemical References |
- Acnevac
- Bacterial Vaccines
- Vaccines
|
| Topics |
- Acne Vulgaris
(immunology, therapy)
- Animals
- Bacterial Vaccines
(administration & dosage, immunology)
- Disease Models, Animal
- Immunotherapy
(methods)
- Macrophages
(immunology)
- Mice
- Mice, Inbred CBA
- Poland
- Propionibacterium
(immunology)
- Propionibacterium acnes
(immunology)
- T-Lymphocytes
(immunology)
- Vaccines
(administration & dosage, immunology)
|
