Effect of Clostridium toxoids, especially of Clostridium perfringens toxoid, on mouse transplanted tumors.

Abstract	The antitumor activities of toxoids of Clostridium perfringens, C. nouyi, C. septicum, and C. tetani were tested against sarcoma-180 and Ehrlich carcinoma. Among them, C. perfringens toxoid showed a high antitumor activity against the growth of the implanted sarcoma-180 ascites form. The results of the inhibiting effect of C. perfringens toxoid on Nakahara-Tokuzen-Fukuoka (NTF) reticulum cell sarcoma and methylcholanthrene-induced fibrosarcoma were also described.
Authors	T Sasaki, G Chihara, N Takasuka, S Suzuki
Journal	Gan (Gan) Vol. 67 Issue 2 Pg. 275-7 (Apr 1976) ISSN: 0016-450X [Print] Japan
PMID	184006 (Publication Type: Journal Article)
Chemical References	Toxoids
Topics	Animals Carcinoma, Ehrlich Tumor (therapy) Clostridium Clostridium perfringens Clostridium tetani Female Fibrosarcoma (therapy) Immunotherapy Lymphoma, Large B-Cell, Diffuse (therapy) Mice Mice, Inbred ICR Neoplasm Transplantation Neoplasms, Experimental (therapy) Sarcoma 180 (therapy) Sarcoma, Experimental (therapy) Toxoids (isolation & purification)

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