Abstract | BACKGROUND: METHODS: A total of 398 patients undergoing 401 SLN biopsy procedures with MBD were retrospectively reviewed and divided into 3 groups based on dye concentration and location of dye injection. Technical success and complication rates were compared. RESULTS: Overall technical success of SLN biopsy was 99.7%. Technical success of SLN mapping with MBD was lowest in the group receiving full strength dye in a peritumoral location (74%) and highest in the group that received very dilute MBD (1.25 mg/mL) in the subareolar location (92%, P = .004). The complication rate was highest in the first group (21%) and lowest in the latter (2%, P = .0003). CONCLUSIONS: Dilute MBD (1.25 mg/mL) successfully maps SLNs with very few complications.
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Authors | Shaheen Zakaria, Tanya L Hoskin, Amy C Degnim |
Journal | American journal of surgery
(Am J Surg)
Vol. 196
Issue 2
Pg. 228-33
(Aug 2008)
ISSN: 1879-1883 [Electronic] United States |
PMID | 18367146
(Publication Type: Journal Article)
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Chemical References |
- Indicators and Reagents
- Methylene Blue
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
(pathology)
- Female
- Follow-Up Studies
- Humans
- Indicators and Reagents
- Lymph Nodes
(pathology)
- Lymphatic Metastasis
- Methylene Blue
(adverse effects)
- Middle Aged
- Retrospective Studies
- Sentinel Lymph Node Biopsy
(methods)
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