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Ichthyosis bullosa of Siemens responds well to low-dosage oral retinoids.

Abstract
Two patients with ichthyosis bullosa of Siemens (IBS) and one patient with bullous ichthyosiform erythroderma of Brocq (BIE) were treated with etretinate. Two additional patients with IBS received acitretin. All the patients had a marked improvement when on retinoids and the maintenance dose required was for IBS 10-25 mg per day. The patient with BIE was on a maintenance dose of 40-60 mg per day.
AuthorsP M Steijlen, R J van Dooren-Greebe, R Happle, P C Van de Kerkhof
JournalThe British journal of dermatology (Br J Dermatol) Vol. 125 Issue 5 Pg. 469-71 (Nov 1991) ISSN: 0007-0963 [Print] England
PMID1836350 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Retinoids
  • Tretinoin
  • Etretinate
  • Acitretin
Topics
  • Acitretin
  • Adult
  • Drug Administration Schedule
  • Etretinate (administration & dosage)
  • Female
  • Hand
  • Humans
  • Ichthyosiform Erythroderma, Congenital (drug therapy, pathology)
  • Leg
  • Male
  • Middle Aged
  • Retinoids (therapeutic use)
  • Skin (pathology)
  • Tretinoin (administration & dosage, analogs & derivatives)

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