Abstract | PURPOSE: MATERIALS AND METHODS: RESULTS: CONCLUSIONS: Overall urine markers did not associate robustly with biopsy findings. The strongest association was a positive association between urine interleukin-8 levels and bladder mast cell count. Patients with ulcer consistently had bladder inflammation but the cystoscopic finding of ulcers was not a sensitive indicator of inflammation on bladder biopsy.
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Authors | Deborah R Erickson, John E Tomaszewski, Allen R Kunselman, Christina M Stetter, Kenneth M Peters, Eric S Rovner, Laurence M Demers, Marcia A Wheeler, Susan K Keay |
Journal | The Journal of urology
(J Urol)
Vol. 179
Issue 5
Pg. 1850-6
(May 2008)
ISSN: 1527-3792 [Electronic] United States |
PMID | 18353383
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Chemical References |
- Biomarkers
- Glycoproteins
- HBEGF protein, human
- Heparin-binding EGF-like Growth Factor
- Intercellular Signaling Peptides and Proteins
- Interleukin-6
- Interleukin-8
- antiproliferative factor APF, human
- ErbB Receptors
- Cyclic GMP
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Topics |
- Adult
- Aged
- Biomarkers
(urine)
- Biopsy, Needle
- Cyclic GMP
(analysis)
- Cystitis, Interstitial
(complications)
- ErbB Receptors
(analysis)
- Female
- Glycoproteins
(urine)
- Heparin-binding EGF-like Growth Factor
- Humans
- Immunohistochemistry
- Intercellular Signaling Peptides and Proteins
(analysis, urine)
- Interleukin-6
(analysis)
- Interleukin-8
(analysis)
- Male
- Mast Cells
(pathology)
- Middle Aged
- Ulcer
(complications, diagnosis)
- Urinary Bladder
(chemistry, pathology)
- Urinary Bladder Diseases
(complications, diagnosis)
- Urothelium
(chemistry)
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