Allergic contact dermatitis from 4-chloro-7-nitrobenzofurazan.

Abstract

A 30-year-old pharmacist suffered from acute allergic contact dermatitis due to 4-chloro-7-nitrobenzofurazan (NBD-Cl). Contact allergy towards this reagent and 2 of its reaction products was proven by patch tests. As NBD-Cl has not been reported as an allergen before, the characteristics of this chemical and its use as an analytical reagent are briefly surveyed. Similarities to dinitrochlorobenzene (DNCB) are pointed out.

• Authors: J Brasch
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 25 Issue 2 Pg. 121-4 (Aug 1991) ISSN: 0105-1873 [Print] England
• PMID: 1834424 (Publication Type: Case Reports, Journal Article)

Chemical References

• Benzofurans
• 7-chloro-4-nitrobenzofuran
• Praziquantel

Topics

• Acute Disease
• Adult
• Benzofurans (adverse effects, chemistry)
• Dermatitis, Contact (drug therapy, etiology)
• Dermatitis, Occupational (chemically induced, drug therapy)
• Female
• Humans
• Praziquantel (adverse effects, chemistry)