[Continuous infusion of baclofen and an antibiotic for treating meningitis related to refilling of an intrathecal infusion pump reservoir].

Abstract

Baclofen via intrathecal infusion pump is a widely used treatment severe spasticity. Complications are rare and usually mild, though they can also be serious. The sudden discontinuation of intrathecal baclofen may have significant adverse effects. We report the case of a 59-year-old man with chronic spasticity and torsion dystonia who developed meningitis due to Staphylococcus epidermidis due to contamination of the intrathecal, infusion pump reservoir during refilling. It was decided to treat the patient by administering vancomycin through the pump, together with the baclofen. We believe that changing the intrathecal perfusion pump is not necessary as the first measure to take in these cases. Combined infusion of baclofen and an antibiotic through the pump makes it possible to maintain antispastic treatment, sterilize the pump reservoir and tubes, and effectively treat infections that develop during use of these systems.

• Authors: A Herranz Gordo, V Villanueva Pérez, A Pérez Cervelló, G Cerdá Olmedo, M A Pallardó López, J A De Andrés Ibáñez
• Journal: Revista espanola de anestesiologia y reanimacion (Rev Esp Anestesiol Reanim) Vol. 55 Issue 1 Pg. 43-6 (Jan 2008) ISSN: 0034-9356 [Print] Spain
• Vernacular Title: Infusión continua de baclofeno con antibiótico para el tratamiento de meningitis asociada a relleno del reservorio de la bomba de perfusión intratecal.
• PMID: 18333386 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anticonvulsants
• Vancomycin
• Baclofen

Topics

• Anti-Bacterial Agents (administration & dosage, therapeutic use)
• Anticonvulsants (administration & dosage, therapeutic use)
• Baclofen (administration & dosage, therapeutic use)
• Dystonia Musculorum Deformans (drug therapy)
• Equipment Contamination
• Home Infusion Therapy (instrumentation)
• Humans
• Infusion Pumps, Implantable (adverse effects)
• Infusions, Parenteral (instrumentation)
• Male
• Meningitis, Bacterial (drug therapy, etiology)
• Middle Aged
• Staphylococcal Infections (drug therapy, etiology)
• Staphylococcus epidermidis
• Vancomycin (administration & dosage, therapeutic use)