Abstract | STUDY DESIGN: Original article. OBJECTIVE: SETTING: Patients with acute spinal cord lesions in the Spinal Unit of Pietra Ligure, Savona, Italy. METHOD: In 4 years, 12 patients have been treated, for a maximum period of 75 days, with dosages ranging from 2 to 4 mg day(-1). RESULTS: All of them reported long-lasting subjective benefits, without side effects, even after the interruption of the therapy. CONCLUSION: The bornaprine treatment, at 2 or 4 mg day(-1) dosage, has been effective and safe to contrast hyperhidrosis, in the acute phase of spinal cord-injured patients. This positive experience would require additional trials and a larger number of cases to gain a more solid support.
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Authors | R Sergi, A Massone, S Moretto, C Oggerino, F Bertolotto, L Losio, M Ottonello |
Journal | Spinal cord
(Spinal Cord)
Vol. 46
Issue 8
Pg. 571-3
(Aug 2008)
ISSN: 1362-4393 [Print] England |
PMID | 18332889
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Bridged-Ring Compounds
- bornaprine
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Topics |
- Adolescent
- Adult
- Aged
- Bridged-Ring Compounds
(therapeutic use)
- Dose-Response Relationship, Drug
- Female
- Humans
- Hyperhidrosis
(drug therapy, etiology)
- Longitudinal Studies
- Male
- Middle Aged
- Spinal Cord Injuries
(complications, drug therapy)
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