HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Efficacy of benzoxazinorifamycins in a mouse model of Chlamydia pneumoniae lung infection.

Abstract
The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight.
AuthorsLee Ann Campbell, Cho-Chou Kuo, Robert J Suchland, David M Rothstein
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 52 Issue 5 Pg. 1855-8 (May 2008) ISSN: 1098-6596 [Electronic] United States
PMID18332169 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Rifamycins
  • KRM 1648
Topics
  • Animals
  • Anti-Bacterial Agents (pharmacology)
  • Chlamydia Infections (drug therapy)
  • Chlamydophila pneumoniae (drug effects)
  • Disease Models, Animal
  • Lung (drug effects, microbiology)
  • Male
  • Mice
  • Microbial Sensitivity Tests
  • Rifamycins (pharmacology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: