Management of common bacterial infections of the skin.

Bacterial skin infections commonly encountered in the community include impetigo, folliculitis/furunculosis, simple abscesses, erysipelas and other nonnecrotizing cellulitis. The review focuses on recent epidemiological, bacteriological and therapeutic advances.
Impetigo and erysipelas occur in about 20 and 1 person/1000/year, respectively. Main risk factors for erysipelas are toe-web intertrigo and lymphedema. The true incidence of furunculosis is unknown, whereas outbreaks in small communities are reported worldwide. Staphylococcus aureus is the predominant pathogen for impetigo and furunculosis, and methicillin-resistant strains play a growing role in both diseases. Erysipelas are mainly caused by streptococci, whereas local complications (i.e. abscesses or blisters) may be due to staphylococci, including methicillin-resistant strains in involved geographic areas. Recent trends for treating impetigo and furunculosis predate community-acquired methicillin-resistant S. aureus. For outbreaks of furunculosis, stringent decolonization measures are showing promise, whereas there is no validated therapeutic regimen for chronic furunculosis. Current trends for erysipelas involve ambulatory treatments and reduced duration of antibiotics.
Despite better epidemiological or bacteriological knowledge of common bacterial skin infections, the exact role of methicillin-resistant staphylococci needs regular surveys in involved geographic areas. Antibiotic treatment must be active on staphylococci and, to a lesser degree, on streptococci.
AuthorsPhilippe Bernard
JournalCurrent opinion in infectious diseases (Curr Opin Infect Dis) Vol. 21 Issue 2 Pg. 122-8 (Apr 2008) ISSN: 0951-7375 [Print] United States
PMID18317033 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Bacterial Agents
  • Anti-Bacterial Agents (therapeutic use)
  • Cellulitis (drug therapy, epidemiology, microbiology)
  • Community-Acquired Infections (microbiology)
  • Erysipelas (drug therapy, epidemiology, microbiology)
  • Furunculosis (drug therapy, epidemiology, microbiology)
  • Humans
  • Impetigo (drug therapy, epidemiology, microbiology)
  • Methicillin Resistance
  • Risk Factors
  • Skin Diseases, Bacterial (drug therapy, epidemiology, microbiology)
  • Staphylococcus aureus (pathogenicity)
  • Streptococcus (pathogenicity)

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