Abstract | UNLABELLED: CONCLUSION: Our results demonstrate the importance of CNTFRalpha-mediated downstream signaling pathways and their functional implications in hepatic cancer cells, thus highlighting a better understanding of the biological roles of CNTFRalpha in human liver abnormalities, including metabolic diseases and hepatocarcinogenesis.
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Authors | Xin Hu, Yingjun Zhao, Xianghuo He, Jinjun Li, Tao Wang, Weiping Zhou, Dafang Wan, Hongyang Wang, Jianren Gu |
Journal | Hepatology (Baltimore, Md.)
(Hepatology)
Vol. 47
Issue 4
Pg. 1298-308
(Apr 2008)
ISSN: 1527-3350 [Electronic] United States |
PMID | 18307269
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Ciliary Neurotrophic Factor
- Ciliary Neurotrophic Factor Receptor alpha Subunit
- Glucose Transporter Type 4
- SLC2A4 protein, human
- STAT3 Transcription Factor
- Janus Kinases
- Protein Serine-Threonine Kinases
- Glucose
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Topics |
- Carcinoma, Hepatocellular
(metabolism)
- Cell Cycle
(physiology)
- Cell Line, Tumor
- Ciliary Neurotrophic Factor
(metabolism)
- Ciliary Neurotrophic Factor Receptor alpha Subunit
(metabolism)
- Glucose
(metabolism)
- Glucose Transporter Type 4
(metabolism)
- Hepatoblastoma
(metabolism)
- Humans
- Janus Kinases
(metabolism)
- Liver
(metabolism)
- Liver Neoplasms
(metabolism)
- Phosphatidylinositol 3-Kinases
(metabolism)
- Plasmids
- Protein Serine-Threonine Kinases
(metabolism)
- RNA Interference
- Receptor Cross-Talk
(physiology)
- STAT3 Transcription Factor
(metabolism)
- Signal Transduction
(physiology)
- Time Factors
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