Abstract |
Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco-lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound-guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500-1,500 MU of BTX per side in 4-6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow-up visits, as well as self-assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism-associated camptocormia.
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Authors | Rainer von Coelln, Armin Raible, Thomas Gasser, Friedrich Asmus |
Journal | Movement disorders : official journal of the Movement Disorder Society
(Mov Disord)
Vol. 23
Issue 6
Pg. 889-92
(Apr 30 2008)
ISSN: 1531-8257 [Electronic] United States |
PMID | 18307265
(Publication Type: Case Reports, Journal Article)
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Copyright | (c) 2008 Movement Disorder Society. |
Chemical References |
- Anti-Dyskinesia Agents
- Botulinum Toxins
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Topics |
- Aged
- Anti-Dyskinesia Agents
(therapeutic use)
- Botulinum Toxins
(therapeutic use)
- Female
- Humans
- Male
- Parkinson Disease
(complications, drug therapy)
- Psoas Muscles
- Treatment Outcome
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