Meta-analysis of tacrolimus ointment for atopic dermatitis in pediatric patients.

Abstract

We evaluated the efficacy and safety of tacrolimus ointment in the treatment of the pediatric patients with atopic dermatitis. Tacrolimus ointment therapy resulted in the remission of atopic dermatitis, this effect of tacrolimus ointment strengths 0.03% and 0.1% were better than those of 1% hydrocortisone acetate and 1% pimecrolimus. Difference between the 0.03% tacrolimus group and the 0.1% tacrolimus group was not statistically significant.

• Authors: Jun Yan, Sheng-Li Chen, Xiao-Lin Wang, Wen Zhou, Feng-shan Wang
• Journal: Pediatric dermatology (Pediatr Dermatol) 2008 Jan-Feb Vol. 25 Issue 1 Pg. 117-20 ISSN: 1525-1470 [Electronic] United States
• PMID: 18304172 (Publication Type: Journal Article, Meta-Analysis, Review)

Chemical References

• Ointments
• Tacrolimus

Topics

• Administration, Topical
• Child
• Child, Preschool
• Confidence Intervals
• Dermatitis, Atopic (diagnosis, drug therapy)
• Evidence-Based Medicine
• Female
• Follow-Up Studies
• Humans
• Infant
• Male
• Ointments (therapeutic use)
• Pediatrics (methods)
• Randomized Controlled Trials as Topic
• Severity of Illness Index
• Tacrolimus (therapeutic use)
• Treatment Outcome