Detection of mechanical ventricular asynchrony by high temporal resolution cine MRI.

Abstract

The purpose was to assess the feasibility of high temporal resolution cine MRI (HTRC-MRI) to detect and to quantify mechanical ventricular asynchrony in patients with left bundle branch block (LBBB). Inter- and intraventricular delays were quantified by HTRC-MRI in 32 patients with (n=17) and without (n=15) LBBB. In patients with LBBB, delays by HTRC-MRI were correlated with echocardiographic parameters using pulsed wave Doppler echocardiography (PW-Echo) and tissue Doppler imaging (TDI-Echo). The interventricular delay by HTRC-MRI was 110+/-50 ms in patients with and -1+/-18 ms in patients without LBBB (P<0.0001). The intraventricular delay was 336+/-86 ms in patients with compared to 40+/-49 ms in patients without LBBB (P<0.0001). A strong correlation (r=0.78, P=0.0002) and good agreement (mean difference: 39+/-36 ms) was found for the interventricular delay between HTRC-MRI and PW-Echo. A good correlation (r=0.66, P=0.0042), but a large discrepancy (mean difference: 257+/-64 ms) was found for the intraventricular delay between HTRC-MRI and TDI-Echo. Detection and quantification of mechanical ventricular asynchrony using HTRC-MRI is feasible. However, further comparison with other imaging modalities is required.

• Authors: Kai Muellerleile, Alexander Stork, Martin Bansmann, Achim Barmeyer, Alexander Dinkelacker, Loant Baholli, Joachim Graessner, Ralf Koester, Gerhard Adam, Gunnar Lund
• Journal: European radiology (Eur Radiol) Vol. 18 Issue 7 Pg. 1329-37 (Jul 2008) ISSN: 0938-7994 [Print] Germany
• PMID: 18299837 (Publication Type: Journal Article)

Topics

• Bundle-Branch Block (physiopathology)
• Chi-Square Distribution
• Echocardiography, Doppler, Pulsed
• Electrocardiography
• Feasibility Studies
• Female
• Heart Failure (diagnosis, physiopathology)
• Heart Ventricles (physiopathology)
• Humans
• Magnetic Resonance Imaging, Cine
• Male
• Middle Aged