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Successful treatment of pulmonary mucormycosis in a renal transplant recipient with limited pulmonary reserve by combined medical and surgical therapy.

Abstract
Mucormycosis is a rare opportunistic fungal infection in renal transplant recipients which is associated with exceedingly high mortality when inadequately treated. Risk factors for this infection include diabetes, neutropaenia and immunosuppression. We report a case of pulmonary mucormycosis in a renal allograft recipient with type 2 diabetes and limited pulmonary reserve. The patient was successfully treated with lobectomy and liposomal amphotericin B with preservation of pulmonary and allograft functions. Early recognition of this infection is warranted before dissemination, which carries a poor prognosis.
AuthorsJordan Y Z Li, Tuck Y Yong, Craig A Jurisevic, Graeme R Russ, David I Grove, P Toby H Coates, Alex P S Disney
JournalHeart, lung & circulation (Heart Lung Circ) Vol. 18 Issue 3 Pg. 226-8 (Jun 2009) ISSN: 1444-2892 [Electronic] Australia
PMID18296117 (Publication Type: Journal Article)
Chemical References
  • Antifungal Agents
Topics
  • Antifungal Agents (therapeutic use)
  • Female
  • Humans
  • Immunocompromised Host
  • Kidney Transplantation (immunology)
  • Lung Diseases, Fungal (drug therapy, immunology, surgery)
  • Middle Aged
  • Mucormycosis (drug therapy, immunology, surgery)
  • Pneumonectomy
  • Recovery of Function

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