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Inhibition of mTOR by sirolimus induces remission of post-transplant lymphoproliferative disorders.

AuthorsMaria Boratyńska, Danuta Smolska
JournalTransplant international : official journal of the European Society for Organ Transplantation (Transpl Int) Vol. 21 Issue 6 Pg. 605-8 (Jun 2008) ISSN: 0934-0874 [Print] Switzerland
PMID18282244 (Publication Type: Case Reports, Letter, Comment)
Chemical References
  • Immunosuppressive Agents
  • Protein Kinases
  • MTOR protein, human
  • TOR Serine-Threonine Kinases
  • Sirolimus
Topics
  • Adult
  • Epstein-Barr Virus Infections (diagnosis, drug therapy, etiology)
  • Humans
  • Immunosuppressive Agents (therapeutic use)
  • Kidney Transplantation (adverse effects)
  • Lymphoma, Large B-Cell, Diffuse (diagnosis, drug therapy, etiology)
  • Lymphoma, T-Cell (diagnosis, drug therapy, etiology)
  • Lymphoproliferative Disorders (diagnosis, drug therapy, etiology)
  • Male
  • Middle Aged
  • Protein Kinases (metabolism)
  • Signal Transduction (drug effects)
  • Sirolimus (therapeutic use)
  • TOR Serine-Threonine Kinases

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