| Abstract | We report a 27-year-old case of juvenile idiopathic arthritis (JIA) having been stopped infliximab during pregnancy. She was safely treated by infliximab therapy with premedications for preventing infusin reactions after her delivery, and then improved in the same manner as when she had been treated with infliximab therapy before pregnancy. As a result, it remains unclear whether or not we can use infliximab to control disease activities during pregnancy. In addition, it is also important to clarify whether or not premedications should be used when resuming infliximab treatment in such patients after pregnancy. These problems still remain controversial. More definitive data are needed in order to allow rheumatologists to better select the optimal TNF-alpha inhibitor therapy when treating pregnant JIA patients. |
| Authors | Yasuhito Nerome, Hiroyuki Imanaka, Yukiko Nonaka, Yumiko Tsuru, Nobuaki Maeno, Tomoko Takezaki, Hirosumi Mori, Harumi Akaike, Tomohiro Kubota, Yoshifumi Kawano, Syuji Takei
(Affiliation: Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. nerome at m.kufm.kagoshima-u.ac.jp)
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| Journal | Modern rheumatology / the Japan Rheumatism Association
(Mod Rheumatol)
Vol. 18
Issue 2
Pg. 189-92
( 2008)
ISSN: 1439-7595 Japan |
| PMID | 18273538
(Publication Type: Journal Article)
|
