[Sentinel lymph node mapping in colorectal cancer: study of 45 cases].

Abstract

OBJECTIVE:

To discuss the sentinel lymph node (SLN) mapping technique in colorectal cancer and its feasibility and utility.

METHODS:

The dye lymphazurin was injected subserosally around the tumor during operation in 43 colorectal cancer, 20 males and 25 females, aged 49.5 (27 - 72) so as to find the SLNs. Fast-frozen pathology and routine pathology were performed too.

RESULTS:

SLN was successfully identified in 42 of the 45 patients, with a successful biopsy rate of 93.3%. In these 45 patients, there were 250 lymph nodes examined, of which 52 nodes were identified as SLNs. The sensitivity was 90.4% (20/22), the specificity was 95.2% [(20 + 20)/42], and the false negative rate was 15% (3/20).

CONCLUSION:

SLN mapping in colorectal cancer plays an important role in diagnosing metastasis of lymph nodes, and can be used to direct the clinical surgery.

• Authors: Yang-de Zhang, Bu-Ning Tian, Hao Li, Deng-Gao Zhai
• Journal: Zhonghua yi xue za zhi (Zhonghua Yi Xue Za Zhi) Vol. 87 Issue 44 Pg. 3125-6 (Nov 27 2007) ISSN: 0376-2491 [Print] China
• PMID: 18269871 (Publication Type: English Abstract, Journal Article)

Chemical References

• Rosaniline Dyes
• iso-sulfan blue

Topics

• Adult
• Aged
• Colorectal Neoplasms (pathology)
• Female
• Humans
• Lymph Nodes (pathology)
• Lymphatic Metastasis (diagnosis)
• Male
• Middle Aged
• Rosaniline Dyes (administration & dosage)
• Sensitivity and Specificity
• Sentinel Lymph Node Biopsy (methods)