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Correction of morphological shifts in experimental syringomyelia.

Abstract
The possibility of correcting morphological shifts in experimental syringomyelia with pyrimidine derivative hydroxymethyluracil (antioxidant with a wide spectrum of biological activities) was studied. Hydroxymethyluracil in a dose of 50 mg/kg prevented the development of morphological shifts characteristic of syringomyelia in the CNS of laboratory animals. Hydroxymethyluracil prevented the development of neurological symptoms and trophic disorders of the skin in rabbits with syringomyelia.
AuthorsT R Mirsaev
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 143 Issue 5 Pg. 648-9 (May 2007) ISSN: 0007-4888 [Print] United States
PMID18239792 (Publication Type: Journal Article)
Chemical References
  • 5-hydroxymethyluracil
  • Pentoxyl
Topics
  • Animals
  • Disease Models, Animal
  • Pentoxyl (analogs & derivatives, therapeutic use)
  • Rabbits
  • Syringomyelia (drug therapy, pathology)

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