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Phellifuropyranone A: a new furopyranone compound isolated from fruit bodies of wild Phellinus linteus.

Abstract
A new furopyranone, phellifuropyranone A, was isolated from fruit bodies of wild Phellinus linteus as well as phelligridin G, and their chemical structures were determined by various spectroscopic methods including measurement of NMR spectra. Phellifuropyranone A together with meshimakobnol A and meshimakobnol B showed antiproliferative activity against mouse melanoma cells and human lung cancer cells in vitro.
AuthorsKazuo Kojima, Takamasa Ohno, Makoto Inoue, Hajime Mizukami, Akito Nagatsu
JournalChemical & pharmaceutical bulletin (Chem Pharm Bull (Tokyo)) Vol. 56 Issue 2 Pg. 173-5 (Feb 2008) ISSN: 0009-2363 [Print] Japan
PMID18239302 (Publication Type: Journal Article)
Chemical References
  • Antibiotics, Antineoplastic
  • Pyrones
  • phellifuropyranone A
Topics
  • Animals
  • Antibiotics, Antineoplastic (isolation & purification, pharmacology)
  • Basidiomycota (chemistry)
  • Cell Line, Tumor
  • Cell Proliferation (drug effects)
  • Drug Screening Assays, Antitumor
  • Fruiting Bodies, Fungal (chemistry)
  • Humans
  • Magnetic Resonance Spectroscopy
  • Mice
  • Pyrones (isolation & purification, pharmacology)
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

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