A 70-year-old man was presented with esophageal and
gastric cancer pointed by his personal doctor in November 2002. Both of the esophageal and
gastric cancer were diagnosed as multiples with cStage II and cStage IA, respectively. In consideration of the patient's quality of life (QOL), chemo-
radiotherapy (CRT) for
esophageal cancer was preceded, and then total
gastrectomy was done. Although
esophageal cancer was responded as being complete response (CR), 14 courses of FP
therapy were added as supportive
chemotherapy. Ten months following CRT,
pericardial effusion was noticed, so that pericardiocentesis was performed. Also
diuretic has been administered up to the present. Nineteen months following CRT,
pleural effusion was noticed and thoracentesis was performed several times into both of the pleural cavities, and that was depending on the degree with
OK-432 infusion. Consequently, the patient has been controlled well. As a treatment for esophageal and gastric double
cancer, we chose CRT rather than
esophagectomy because of the excessive invasiveness. Despite of CR, we have had a difficulty with pleural and
pericardial effusions due to the late toxicity of
radiotherapy. We need to pay attention to the late toxicity in the case of long-term survival following CRT.