[Maxillary sinus cancer review in 23 patients treated with postoperative radiotherapy].

Abstract

OBJECTIVE:

To describe the survival and outcome of maxillary sinus cancer in patients managed with surgery and post-operative radiotherapy during the last 10 years in our hospital.

PATIENTS AND METHOD:

Descriptive, retrospective, non-randomized study of 23 patients with cancer of the maxillary sinus managed at the Vigo University Hospital Complex, Spain, with radical surgery and post-operative radiotherapy, between 1995 and 2004.

RESULTS:

The 3-year actuarial survival was 47.8% and the adjusted actuarial survival was 60.8%. Permanent local tumour control was achieved in 60.8% of cases (14/23). Local tumour recurrence was the main cause of treatment failure (33.3%; 4/12). The most significant prognostic factors affecting local tumour control and survival were: clinical stage (P< .031), suprastructural location of the tumour (P< .001), and presence of positive resection margins (P< .001).

CONCLUSIONS:

Local recurrence was found to be very high and generally the main cause of death. New treatment protocols should be assessed.

• Authors: Rubén D Manrique, Leopoldo G Deive, Michel A Uehara, Roslyn K Manrique, José L Rodríguez, Carmelo Santidrian
• Journal: Acta otorrinolaringologica espanola (Acta Otorrinolaringol Esp) Vol. 59 Issue 1 Pg. 6-10 (Jan 2008) ISSN: 0001-6519 [Print] Spain
• Vernacular Title: Revisión del cáncer de seno maxilar en 23 pacientes tratados con radioterapia postoperatoria.
• PMID: 18215383 (Publication Type: English Abstract, Journal Article)

Topics

• Aged
• Aged, 80 and over
• Combined Modality Therapy
• Female
• Humans
• Male
• Maxillary Sinus Neoplasms (radiotherapy, surgery)
• Middle Aged
• Neoplasm Staging
• Postoperative Care
• Retrospective Studies