[Efficacy of dapsone in disseminated granuloma annulare: a case report and review of the literature\].

Abstract

Granuloma annulare is a dermatosis of unknown cause that is generally self-limiting and has several clinical forms of presentation. It may be associated with pruritus or present asymptomatically. The disseminated variant of the disease accounts for 15 % of all cases. Most authors consider that the duration of this form is longer and that treatment response is worse than for localized forms. A range of therapeutic options have been tried for this disease with a wide range of outcomes. We present a patient with disseminated granuloma annulare who started treatment with dapsone after several therapeutic failures. With dapsone therapy, her cutaneous symptoms showed a clear improvement without any relevant side effects. We then review reports in the literature of cases of disseminated granuloma annulare treated with dapsone.

• Authors: E Martín-Sáez, M Fernández-Guarino, R Carrillo-Gijón, E Muñoz-Zato, P Jaén-Olasolo
• Journal: Actas dermo-sifiliograficas (Actas Dermosifiliogr) 2008 Jan-Feb Vol. 99 Issue 1 Pg. 64-8 ISSN: 0001-7310 [Print] Spain
• Vernacular Title: Eficacia de la dapsona en el granuloma anular diseminado: presentación de un caso y revisión de la literatura.
• PMID: 18206089 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Dapsone

Topics

• Aged
• Dapsone (therapeutic use)
• Female
• Granuloma Annulare (drug therapy)
• Humans