Atrophy of the intrinsic musculature of the hands associated with the use of botulinum toxin-A injections for hyperhidrosis: a case report and review of the literature.

Abstract

Botulinum toxin type A (BTX-A) has been used therapeutically for the treatment of spastic disorders for many years. More recently, the therapeutic utility of BTX-A in the treatment of hyperhidrosis has been recognised. While studies have reported on the efficacy of BTX-A in managing hyperhidrosis, long term data are required in order for the treatment implications to be fully appreciated. We report on a case of severe atrophy of the intrinsic muscles of the hands in a patient treated with intra-palmar BTX-A (Dysport, Speywood, UK) injections for hyperhidrosis. To our knowledge this has not been described in the literature before.

• Authors: G E Glass, M Hussain, A N M Fleming, B W E M Powell
• Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS (J Plast Reconstr Aesthet Surg) Vol. 62 Issue 8 Pg. e274-6 (Aug 2009) ISSN: 1878-0539 [Electronic] Netherlands
• PMID: 18203669 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Neurotoxins
• Botulinum Toxins, Type A

Topics

• Adolescent
• Botulinum Toxins, Type A (administration & dosage, adverse effects)
• Female
• Humans
• Hyperhidrosis (drug therapy)
• Injections, Intradermal
• Muscular Atrophy (chemically induced)
• Neurotoxins (administration & dosage, adverse effects)
• Treatment Outcome