Successful multimodal treatment in a patient with thymoma accompanied by hepatic metastasis.

Abstract

Despite a benign histologic appearance, thymomas have metastatic potential. Here we report a case of a patient with a Masaoka stage IVb thymoma who was successfully treated using a multimodal strategy including systemic chemotherapy, radiofrequency ablation, and thoracic surgery. Despite complete remission after treatment, the patient developed myasthenia gravis with ptosis and neck drop symptoms. Hepatic metastasis of thymoma is a relatively rare occurrence and, to the best of our knowledge, this is the first report about the application of radiofrequency ablation to thymoma.

• Authors: Shigenori Hoshino, Mitsugi Furukawa, Kazumi Aragane, Masayoshi Horimoto, Kunio Suzuki, Hiroyuki Shiono, Masato Minami, Meinoshin Okumura, Takashi Kijima, Ichiro Kawase
• Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer (J Thorac Oncol) Vol. 3 Issue 1 Pg. 98-100 (Jan 2008) ISSN: 1556-1380 [Electronic] United States
• PMID: 18166848 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Antineoplastic Agents, Phytogenic
• Etoposide
• Cisplatin

Topics

• Antineoplastic Agents (therapeutic use)
• Antineoplastic Agents, Phytogenic (therapeutic use)
• Biopsy, Needle
• Catheter Ablation (methods)
• Cisplatin (therapeutic use)
• Combined Modality Therapy
• Drug Administration Schedule
• Etoposide (therapeutic use)
• Female
• Follow-Up Studies
• Humans
• Liver Neoplasms (pathology, surgery)
• Middle Aged
• Myasthenia Gravis (drug therapy, pathology)
• Neoplasm Metastasis
• Neoplasm Staging
• Positron-Emission Tomography
• Thymectomy
• Thymoma (classification, diagnostic imaging, drug therapy, pathology, surgery)
• Thymus Neoplasms (classification, diagnostic imaging, drug therapy, pathology, surgery)
• Time Factors
• Tomography, X-Ray Computed
• Treatment Outcome