Somnambulism induced by quetiapine: two case reports and a review of the literature.

Abstract

Somnambulism, a previously unreported side effect of quetiapine, is described in two cases. Both cases involved individuals who had no prior or family history of somnambulism and had attention-deficit/hyperactivity disorder. The possible significance of this will also be discussed. Somnambulism is a common parasomnia that reflects an impairment in the normal mechanisms of arousal from sleep in which motor behaviors are activated without full consciousness. Motor behaviors are initiated during deep non-rapid eye movement or slow-wave sleep (stages 3-4), and may be limited to relatively simple manifestations, such as sitting up, fumbling with objects or bedclothes, or mumbling.

• Authors: Zeba Hasan Hafeez, Constance M Kalinowski
• Journal: CNS spectrums (CNS Spectr) Vol. 12 Issue 12 Pg. 910-2 (Dec 2007) ISSN: 1092-8529 [Print] United States
• PMID: 18163036 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antipsychotic Agents
• Dibenzothiazepines
• Quetiapine Fumarate
• Magnesium

Topics

• Adolescent
• Antipsychotic Agents (adverse effects)
• Dibenzothiazepines (adverse effects)
• Humans
• Lower Extremity (physiopathology)
• Magnesium
• Male
• Middle Aged
• Polysomnography
• Quetiapine Fumarate
• Seizures (physiopathology)
• Somnambulism (chemically induced)