Abstract | PURPOSE: METHODS: To describe fibrin glue manufacture, development of a device to test the glued perforated corneal area resistance, subsequent experimental investigations of the use of the fibrin glue in corneal perforations, reporting its efficacy, mechanical resistance experiments and histological study. Finally, the medical literature basis is searched to propose studies on the use of fibrin as a temporary basal membrane on non-perforated corneal surfaces like non-infectious corneal ulcers and on post- photorefractive keratectomy corneal surfaces. RESULTS: The development of fibrin glue, the device for resistance experiments, the efficacy, resistance and histological studies on fibrin glue used for sealing corneal perforations are reported as well as the scientific literature basis for the proposed studies on the use of fibrin as a temporary basal membrane on non-perforated corneas like non-perforated corneal ulcers and photorefractive keratectomy corneal surfaces. CONCLUSION:
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Authors | José Américo Bonatti, Samir Jacob Bechara, Marcelo Wesley Lopes Dall'Col, Fernando Betty Cresta, Pedro Carlos Carricondo, Newton Kara-José |
Journal | Arquivos brasileiros de oftalmologia
(Arq Bras Oftalmol)
2007 Sep-Oct
Vol. 70
Issue 5
Pg. 884-9
ISSN: 0004-2749 [Print] Brazil |
PMID | 18157320
(Publication Type: Journal Article, Review)
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Chemical References |
- Fibrin Tissue Adhesive
- Membranes, Artificial
- Tissue Adhesives
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Topics |
- Animals
- Brazil
- Corneal Diseases
(drug therapy, surgery)
- Corneal Injuries
- Corneal Ulcer
(drug therapy)
- Dogs
- Fibrin Tissue Adhesive
(therapeutic use)
- Humans
- Intraocular Pressure
(drug effects)
- Lasers, Excimer
- Membranes, Artificial
- Models, Animal
- Photorefractive Keratectomy
- Research Design
- Tissue Adhesives
(therapeutic use)
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