Bucolome in prevention of hyperbilirubinaemia in preterm infants.

Abstract

Fifty preterm babies were randomly assigned to a group given oral bucolome (30 mg/kg per day for 5 days) and a control group. Serum bilirubin levels of the treated infants from day 4 onwards were consistently lower than those of the control infants. 3 of the 25 control infants (but none of the 25 treated infants) had bilirubin levels greater than 18 mg/100 ml (308 mumol/l) and required exchange transfusion. No sedation or drowsiness was observed in the infants given bucolome, and though the drug caused some vomiting, weight gains were unaffected.

• Authors: G Segni, G Polidori, C Romagnoli
• Journal: Archives of disease in childhood (Arch Dis Child) Vol. 52 Issue 7 Pg. 549-50 (Jul 1977) ISSN: 1468-2044 [Electronic] England
• PMID: 18116 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Barbiturates

Topics

• Barbiturates (therapeutic use)
• Clinical Trials as Topic
• Female
• Humans
• Infant, Newborn
• Infant, Premature, Diseases (prevention & control)
• Jaundice, Neonatal (drug therapy, prevention & control)
• Male